Increasing levels of eNAMPT enzymes in molecular bubbles in the blood delays aging and increases health span and lifespan in mice.

Scientists found NMN administration preserved mitochondrial health and prevented heart failure in mice deficient in a molecule that makes them susceptible to heart disease.

Scientists find NMN improves depression-like behavior, displayed as immobility in swim tests, and cellular energy production in mice.

Scientists provide genetic evidence indicating NMN supplementation promotes rejuvenation of blood vessels providing nutrients to the brain.

A study indicates NMN supplementation and exercise can reverse glucose intolerance, where sugars accumulate in the blood from food intake, but these two interventions have tissue-specific effects on the function of the mitochondria.

NMN mitigates age-related cellular changes in aged mice intestine stem cells that are caused by the decreased cell proliferation from reduced activation of the Lgr5 gene.

The loss of NAD+ levels leads to rapid neurodegeneration in the eye and the loss of vision, but scientists discovered that replenishing the molecule can prevent the adverse effects and restore vision.

Scientists find injecting mice with NAD+ booster protects against hearing loss through the activation of SIRT3, a protein that prevents damage to nerve connections between the ear and the brain.

Scientists found that giving diabetic mice NMN can reverse symptoms of diabetes and the method provides critical insights into a potential intervention against type 2 diabetes.

Scientists showed increasing NAD+ levels promotes longevity and prevents age-related metabolic decline with improved cellular stress signaling in roundworms.