The Official Info Source for Nicotinamide Mononucleotide

Astronauts’ exposure to weightlessness during spaceflight precipitates bone degradation and proneness to fracture, however, nicotinamide mononucleotide (NMN) restores bone strength in a rat model for space travel.

Creatine – a commonly used workout supplement – has been shown to enhance memory performance in healthy adults, particularly among seniors.

Supplementing stroke-damaged mice with berberine decreases brain inflammation and improves neurological function, possibly via the gut.

Cycloastragenol – a plant compound – is capable of eliminating aged (senescent) human cells in culture and senescent cells in mice, leading to improved physical aging.

The non-profit organization — Alliance for Longevity Initiatives (A4LI) — proposes a strategy to accelerate FDA approval of anti-aging drugs, improve quality of life, and reduce healthcare costs (without raising taxes) in the face of a rapidly aging nation.

Scientists found that old mice repeatedly exposed to bacterial components to induce infection and inflammation suffered from impaired learning and memory, with implications for frequent colds and viruses in the elderly.

Japanese researchers from Shiga University of Medical Science show that, while ketogenesis is essential for mouse survival, a low-carb ketogenic diet shortens lifespan in middle-aged and old mice.

This high-fat, low-carb diet prevents memory decline and anxious behavior in aging mice while reducing inflammation and elevating “good” HDL cholesterol.

While the Mediterranean diet reduces artery stiffness in middle-aged adults with high abdominal fat, the Green Mediterranean reduces it further, indicating a potential reversal of cardiovascular aging.

Temple University researchers find that treating an Alzheimer’s disease mouse model with existing drugs used for altitude sickness and glaucoma prevents cognitive decline and removes sticky Aꞵ proteins in brain vasculature.

Ganoderma lucidum (GL) fungus, referred to as reishi or lingzhi in Asia, improves testosterone levels, sexual function, and fertilization rates among middle-aged male mice.

Even with worries about social security and a decline in workforce numbers, an aging US population may not ruin the US economy because of more capital for workers and potential immigration.

Rapamycin restores lower limb blood flow in aged mice and mouse models for Alzheimer’s and atherosclerosis with implications for treating neurodegeneration and heart disease.

The biological age of older women significantly declined after undergoing a dietary and lifestyle program designed to increase DNA methylation — molecular tags on DNA that influence gene activation patterns.

Older individuals on an anti-aging senolytic diet consisting of strawberries and capers have reduced “bad” cholesterol and inflammation.