The Vitalists argue that society needs a revolution for the sake of lifespan extension, and a growing number of scientists, investors, and politicians are taking them seriously.
Seragon Biosciences has completed one of the most comprehensive preclinical studies to date, finding that its aging intervention candidate SRN-901 drastically prolongs lifespan and healthspan.
Naturally produced molecules mediate metabolic cues that link calorie restriction to pro-longevity effects, and supplementing with them may aid in extending healthy lifespan.
Fructooligosaccharides (FOS) and ellagic acid (EA) enhance muscular endurance and mass by targeting gut bacteria urolithin A biosynthesis in mice.
A direct comparison of NAD+ precursors in humans shows that NMN and NR double circulating NAD+ after two weeks of supplementation, while Nam does not.
Metformin—a repurposed FDA-approved drug—prevents impairments in visual processing in aged mice.
Spaceflight exposes astronauts to age-inducing environmental stressors, and a new study finds that, on average, it accelerates biological age—an assessment reflecting how well cells are aging.
While urolithin A and spermidine both target cellular maintenance, urolithin A targets the function of the cell’s powerhouses (mitochondria) more, and spermidine has broader pro-longevity effects.
Preserving mitochondrial health may be the key to preventing cellular aging, and scientists reveal tactics for doing so, according to their new theory.
Rather than lifestyle, substantially extending lifespan may involve reducing cellular damage and increasing damage removal, potentially with known longevity interventions.
Seragon Biosciences has completed one of the most comprehensive preclinical studies to date, finding that its aging intervention candidate SRN-901 drastically prolongs lifespan and healthspan.
Naturally produced molecules mediate metabolic cues that link calorie restriction to pro-longevity effects, and supplementing with them may aid in extending healthy lifespan.
Fructooligosaccharides (FOS) and ellagic acid (EA) enhance muscular endurance and mass by targeting gut bacteria urolithin A biosynthesis in mice.
A direct comparison of NAD+ precursors in humans shows that NMN and NR double circulating NAD+ after two weeks of supplementation, while Nam does not.
Metformin—a repurposed FDA-approved drug—prevents impairments in visual processing in aged mice.
Spaceflight exposes astronauts to age-inducing environmental stressors, and a new study finds that, on average, it accelerates biological age—an assessment reflecting how well cells are aging.
While urolithin A and spermidine both target cellular maintenance, urolithin A targets the function of the cell’s powerhouses (mitochondria) more, and spermidine has broader pro-longevity effects.
Preserving mitochondrial health may be the key to preventing cellular aging, and scientists reveal tactics for doing so, according to their new theory.
Rather than lifestyle, substantially extending lifespan may involve reducing cellular damage and increasing damage removal, potentially with known longevity interventions.
Inhibiting a key age-associated cellular signaling enzyme, called mTOR (mechanistic target of rapamycin), counteracts DNA damage and immune system aging in humans.
NMN Counteracts Muscle and Liver Aging in New Multi-Study Analysis
The Vitalists argue that society needs a revolution for the sake of lifespan extension, and a growing number of scientists, investors, and politicians are taking them seriously.
Naturally produced molecules mediate metabolic cues that link calorie restriction to pro-longevity effects, and supplementing with them may aid in extending healthy lifespan.
Fructooligosaccharides (FOS) and ellagic acid (EA) enhance muscular endurance and mass by targeting gut bacteria urolithin A biosynthesis in mice.
A direct comparison of NAD+ precursors in humans shows that NMN and NR double circulating NAD+ after two weeks of supplementation, while Nam does not.
Metformin—a repurposed FDA-approved drug—prevents impairments in visual processing in aged mice.
Spaceflight exposes astronauts to age-inducing environmental stressors, and a new study finds that, on average, it accelerates biological age—an assessment reflecting how well cells are aging.
While urolithin A and spermidine both target cellular maintenance, urolithin A targets the function of the cell’s powerhouses (mitochondria) more, and spermidine has broader pro-longevity effects.
Preserving mitochondrial health may be the key to preventing cellular aging, and scientists reveal tactics for doing so, according to their new theory.
Rather than lifestyle, substantially extending lifespan may involve reducing cellular damage and increasing damage removal, potentially with known longevity interventions.
Alpha-ketoglutarate improves memory-formation capacity in mice that model brain aging.
A new primate study shows long-term calorie restriction preserves brain white matter by slowing age-related changes in oligodendrocytes and microglia.
According to a new study, whether from exercise or supplementation, increased levels of β-hydroxybutyrate (a molecule primarily released from the liver during fasting or aerobic exercise) improve cognition in old mice.
Stem cell–derived vesicles rejuvenate aging pancreatic β cells, restore insulin secretion, and reverse diabetes in old mice by reducing cellular senescence and improving mitochondrial function.