DHA supplementation improves the memory of aged rats fed a high-fat diet while restoring insulin levels and reducing primary drivers of aging — inflammation and oxidative stress.
In a fresh-off-the-press interview, Dr. Sinclair dropped a tantalizing tidbit: his lab's got the data to confirm that NMN is the next big thing in the longevity game—for mice, at least.
Treating male diabetic rats with curcumin and vitamin E improves sperm health and lowers oxidative stress in sperm cells.
A nicotinamide mononucleotide (NMN)-loaded hydrogel dressing — a wound-covering matrix mostly composed of water — speeds diabetic wound healing and restores skin thickness in a diabetic skin wound mouse model.
Research from Harvard Medical School and Duke University School of Medicine shows that exposure to youthful circulation extends the maximum and average lifespan of old mice.
Researchers show that pea protein combined with the fiber inulin increases muscle mass, inhibits gene activity for muscle breakdown, and enhances the function of the cell powerhouse — mitochondria — in muscle of aged rats.
NMN reduces brain damage caused by stroke and prevents leakage of the blood-brain barrier — a barrier that keeps toxins out of the brain but deteriorates with age — in aged mice.
Those taking nicotinamide mononucleotide (NMN) do so to prevent or reverse aging and promote physical function.
Researchers find that injecting aged mice with particles secreted from stem cells (extracellular vesicles) enhances memory.
Scientists lower blood pressure and improve blood vessel health with a plum juice concentrate called bainiku-ekisu in a mouse model for hypertension (high blood pressure).
NMN and NR similarly rejuvenate human blood vessel cells by preventing oxidative stress — a driver of aging — and restoring nitric oxide, critical for blood vessel function.
The FDA cited “competing agency priorities” in a recent letter describing why it hasn’t reached a substantive decision pertaining to a citizen petition about NMN in dietary supplement products.
So far, human trials have demonstrated the safety of nicotinamide mononucleotide (NMN) along with its enhancement of physical functioning and insulin sensitivity.
Fucoidan — abundant in brown algae seaweed — reduces brain inflammation, increases neuron production, and improves memory in a mouse model for inflammation-induced brain aging.
Researchers find that diabetes — a leading cause of shortened lifespan — could potentially be treated by insulin-secreting human cells activated by music.