Research published in Frontiers in Pharmacology shows that berberine reduces toxic protein accumulation in Alzheimer’s mice, providing new insights for future drug development in treating neurodegenerative diseases.
A study in Science identifies genes related to immunity, DNA repair, and nutrient sensing as genetic drivers for rockfish lifespans exceeding 200 years.
Already known to have brain-protective and anti-inflammatory properties in mice and humans, minocycline extends lifespan up to almost 50% in a common lab animal used to study aging.
Researchers find a potential therapeutic strategy for preserving mouse heart tissue after impaired blood flow by activating a longevity-associated protein called TERT.
The National Institute of Health (NIH) Common Fund’s Cellular Senescence Network (SenNet) program awarded $125 million among 16 university teams to study non-replicating and aging-related “senescent” cells.
Research shows that antioxidant compounds in green tea called catechins increased the longevity and stress resistance of the roundworm C. elegans.
Researchers have fused antibodies with a cell toxic compound to remove non-proliferating (senescent) cells without harming non-senescent cells.
Mayo Clinic researchers cleared non-proliferating (senescent) cells with the combo of Dasatinib and Quercetin to accelerate fracture healing
Dr. Dudley Lamming discusses his recent work on how fasting, not merely reducing calorie intake, drives metabolic benefits and promotes longevity in mice.
Long and healthy lifespans require NAD+, so why do levels of this vital molecule drop as we age?
A University of Wisconsin animal study shows that extended periods without eating, not decreased calorie intake, drive aging-resistant metabolic benefits.
In mice, high-fat diets cause the degradation of conductive nerve coatings called myelin, but they can be regenerated by restoring NAD+ levels with the precursor NMN.
Telomere shortening is a well-known and widely-used marker for biological aging. But should it be?
Taking NMN by under-the-skin injections or oral consumption improves immune cells that attack cancer and virally infected cells in mice.