The antioxidant supplement pyrroloquinoline quinone disodium salt (PQQ) improves complex and verbal memory in older adults along with cognitive responses in younger adults.
Treating immune cells that target hepatitis B with nicotinamide mononucleotide (NMN) restores their DNA repair mechanisms and antiviral function.
The amino acid D-serine is reduced in older individuals, and D-serine supplementation improves the memory of aged mice.
Alcohol degrades the intestines' ability to block bacteria and toxic metabolites from crossing into blood circulation, yet nicotinamide riboside (NR) restores the gut in mice.
Urolithin A moderately extends the lifespan of normal mice and reduces Alzheimer’s mouse model pathology.
The petition requests the FDA reverse its decision to reject NMN’s classification as a dietary ingredient and to use enforcement discretion.
Both a low phosphate diet and Velphoro — a phosphate lowering drug — mitigate features of muscle aging, including muscle strength and physical performance, in mice.
Endurance exercise is associated with reduced senescent cells – non-proliferating cells that evade programmed death and emit inflammatory molecules – in the colon of aged runners.
Vesicles secreted from NMN-treated stem cells improve heart function while promoting blood vessel formation and reducing tissue damage after myocardial infarction (heart attack) in rats.
France has produced the two documented longest-living people in world history, likely due to contributing factors like healthy dietary choices and free healthcare.
Senescent age-associated cells worsen survival probability in glioblastoma cancer patients, yet removing senescent cells significantly increases the lifespan of mice with glioblastoma.
Injecting luteolin reduces high blood pressure (hypertension) by reducing inflammation in a brain region that controls blood pressure in rats.
Naringin – a flavor compound found in grapefruit – protects against damage-induced lung aging and may enhance longevity by activating SIRT1, a protein involved in decreasing cellular stress and known to be anti-aging.
Scientists show that phthalate — a chemical used in toys, food packaging, and shampoo — induces features of oocyte aging that can be reversed by NMN.
Scientists show that age-related bone loss can be recovered by the immunosuppressant drug rapamycin, which promotes mitochondrial health and reduces bone cell death in mice.