NR supplementation improves mitochondrial function and affects inflammatory response in heart failure patients

A study indicates administering NR provides a heart failure therapy by reducing inflammation and improving cardiac function.

How Increasing NAD+ May Protect Humans From Heart Failure

Cardiovascular

Scientists treated old mice with the molecules SS-31 and NMN (nicotinamide mononucleotide) separately to improve different heart functions and when delivered together these molecules acted synergistically to recapitulate the function and metabolism of young hearts.

Two molecules when taken in combination act synergistically to recapitulate young heart function in older hearts by targeting mitochondria.

Two Molecules Improve Heart Function

NAD+ precursor decreases atrial fibrillation susceptibility and duration in mice

NR decreases the susceptibility for atrial fibrillation along with its duration.

Nampt/NAD+ Axis may be a Therapeutic Target for Atrial Fibrillation

Researchers from China find nicotinamide mononucleotide (NMN) protects tissue and improves damage in mice following intracerebral hemorrhage.

Neurological

Researchers from the University of Maryland and the Veterans Affairs Maryland Health Center recently found that NMN improves mitochondrial NAD+ metabolism and mitochondrial health via SIRT3 in ischemic mice.

How NAD+ Levels Affect Mitochondrial Health After Cerebral Ischemia

A study reported functional training and traditional training exercise routines improved strength and agility in aging women when compared to stretching alone.

Functional and Traditional Training (How Aging Women Can Improve Strength)

This treatment is a promising strategy to attenuate damage and boost protection in aged hearts

NMN and melatonin administration in combination mitigates rat heart damage following ischemia and reperfusion.

Scientists from the University of Oklahoma Health Sciences Center conduct a study demonstrating nicotinamide mononucleotide (NMN) supplements improve brain blood vessel generation (crebromicrovascular angiogenesis) in aged rats.

Scientists conduct a study demonstrating NMN supplements improve brain blood vessel generation (crebromicrovascular angiogenesis) in aged rats.

Data suggest NMN administration improves brain blood vessel dilation (vasodilation) and blood flow to the brain

Scientists conduct a study that NMN administration improves brain function in mice.  The data suggest NMN improves blood vessel dilation and blood flow to the brain.

NMN Improves Cognitive Function in Mice

Scientists from the University of Rochester Medical Center find nicotinamide mononucleotide (NMN) confers heart protection in mice.

Studies

NEWS

The Combination of Melatonin and NMN Protects the Aged Heart from Injury