Studies - Cardiovascular




The Nampt/NAD+ Axis may be a Potent Therapeutic Target for Atrial Fibrillation

NAD+ precursor decreases atrial fibrillation susceptibility and duration in mice


The Molecules SS-31 and NMN Synergistically Improve Aged Heart Function

Scientists treated old mice with the molecules SS-31 and NMN (nicotinamide mononucleotide) separately to improve different heart functions and when delivered together these molecules acted synergistically to recapitulate the function and metabolism of young hearts.


Boosting NAD+ Improves Mitochondrial Health Following Cerebral Ischemia

Researchers from the University of Maryland and the Veterans Affairs Maryland Health Center recently found that NMN improves mitochondrial NAD+ metabolism and mitochondrial health via SIRT3 in ischemic mice.


Boosting NAD+ Levels Improves Heart Function in Mice with Heart Failure

A study from Duke University indicated that NMN supplementation improves function in mice with heart disease via boosting NAD+ levels and SIRT3 activity.


NMN Administration Promotes Mitochondrial Health and Prevents Heart Failure

Scientists found NMN administration preserved mitochondrial health and prevented heart failure in mice deficient in a molecule that makes them susceptible to heart disease.


NMN Reverses Vascular Dysfunction From Aging in Mice

Supplementing mice with nicotinamide mononucleotide (NMN) reverses age-related artery dysfunction, a key contributor to cardiovascular disease.


NMN Protects the Heart from Ischemia and Reperfusion in Mice

Ischemia, the inadequate blood supply to body parts, can lead to life-threatening conditions. Scientists found that NMN may be a new intervention for it.