Scientists from Harvard Medical School found that NAD+ directly regulates protein interactions, which may protect the cell against cancer, radiation and aging.

An international team of scientists from Europe, the US and Australia revealed that boosting NAD+ mitigates DNA damage and improves survival in animals with neurological defects in a 2016 study.

Scientists from multiple institutions, including Baylor College of Medicine, MD Anderson Cancer Center, and the University of Pennsylvania perform experiments on mice, indicating nicotinamide mononucleotide (NMN) supplementation ameliorates cellular conditions associated with reduced DNA integrity and counteracts liver disease.