Studies - Longevity




Enzyme Regulating NAD+ Keeps Mouse Cells Replicating Under Stress

Genetically modified mouse cells with artificial activation of a nicotinamide adenine dinucleotide (NAD+) regulating enzyme are protected from cessation of cell proliferation induced by stress, maintaining healthy aging.


NAD+ Keeps the Mouse Body Clock Young to Counter Aging

Boosting nicotinamide adenine dinucleotide (NAD+) levels restores improves circadian rhythms in old mice through youthful gene activation and metabolic patterns, revealing that NAD+ governs both behavior and metabolic health.


Enzyme in Blood from Young Mice Helps Delay Aging and Extends Lifespan in Aged Mice

Increasing levels of eNAMPT enzymes in molecular bubbles in the blood delays aging and increases health span and lifespan in mice.


NMN Suppresses Age-Induced Changes in Intestinal Stem Cells of Mice

NMN mitigates age-related cellular changes in aged mice intestine stem cells that are caused by the decreased cell proliferation from reduced activation of the Lgr5 gene.


NAD+ Activates Proteins and Cellular Pathways to Promote Longevity

Scientists showed increasing NAD+ levels promotes longevity and prevents age-related metabolic decline with improved cellular stress signaling in roundworms.

DNA Repair

NAD+ Increases Healthspan and Lifespan Through DNA Repair in Animals with Neurological Defects

An international team of scientists from Europe, the US and Australia revealed that boosting NAD+ mitigates DNA damage and improves survival in animals with neurological defects in a 2016 study.


Nicotinamide Mononucleotide Supplementation Extends the Healthspan in Mice

Boosting NAD+ level with natural compound, NMN, for 12 months reduces signs of aging in healthy mice