Studies
Insilico Partners with Taisho to Make Anti-Aging Drugs with AI
The collaboration sets a precedent in longevity drug discovery and development.
An Ancient Therapeutic Compound Improves Energy Production in Aged Muscle
Urolithin A bolstered cellular energy production, NAD+ levels, and blood vessel formation in aged muscles of mice.
Researchers Pinpoint the Cause of Childhood-Blindness Disease
The NAD+-consuming enzyme SARM1 is a therapeutic candidate for retinal diseases and vision loss.
NR Supplementation Alleviates Kidney Disease in the Short-Term for Mice
An orally available NAD+ precursor NR relieves acute kidney injury but not chronic kidney disease.
Challenging the Current Thinking on NR Supplementation
Researchers discuss data challenging the proposal that NR supplementation improves the function of the cell’s powerhouse, the mitochondria, in humans.
The Promise of Therapeutically Targeting Sirtuins in Lung Fibrosis
Potential therapeutic modulations of Sirtuins through synthetic- and plant-derived compounds can help design new-generation cheap, non-toxic Sirtuin-based drugs against lung fibrosis.
Scientists From China Improve Bone Formation Deficiencies in Glucocorticoid-Induced Osteoporosis
Scientists at Nanchang University discovered NMN may be a therapeutic option for glucocorticoid-induced osteoporosis.